The global Tangential Flow Filtration Market in terms of revenue was estimated to be worth $1.9 billion in 2023 and is poised to reach $3.6 billion by 2028, growing at a CAGR of 13.5% from 2023 to 2028 according to a new report by MarketsandMarkets™. The TFF market is expected to have a growth rate of 13.5% during 2023-2028. Increasing benefits over normal flow filtration, the introduction of single-use technologies, adoption of gamp guidelines, increasing investment by pharmaceutical companies, growing biopharmaceutical industries are some of the factors that will accelerate the growth of the Tangential Flow Filtration Market in the forecast period.

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In 2022, the systems segment accounted for the largest share of the product segment in the Tangential Flow filtration market.

On the basis of products, the tangential flow filtration market is segmented into systems, membrane filters, and other tff products. In 2022, the systems segment accounted for the largest share of the market and is expected to grow at the highest CAGR during 2023-2028. Tangential filtration systems consist of automated and mechanical filtration systems. These systems provide maximum operational reliability. Some of the benefits associated with these systems include a high retention rate, less consumption of energy, low cost, and reduced cross-contamination risk. With the help of such systems, pharmaceutical companies can achieve the highest quality products. The systems segment is further segmented into single-use and reusable systems. Single-use systems are gaining importance in separation and purification applications. Developments in research techniques and increased demand for more specificity in the filtration process are increasing the adoption of single-use technologies in many small-scale biopharmaceutical processes.

In 2022, the microfiltration segment accounted for the largest share of the technique segment in the Tangential Flow filtration market.

On the basis of technique, the tangential flow filtration market is segmented into microfiltration, ultrafiltration, nanofiltration, and other techniques. In 2022, the microfiltration segment accounted for the largest market share. The filters used in this technique can be in a submerged configuration or a pressure vessel configuration; they can be hollow fibers, flat, sheet, tubular, or spiral.

In 2022, the Asia Pacific region is the fastest-growing region of the Tangential Flow filtration market.

The tangential flow filtration market is divided into five regions including, North America, Europe, Asia Pacific, Latin America and Middle East and Africa. The Asia Pacific market is expected to register the highest CAGR during 2023-2028. Factors responsiblr for the growth includes, unique industry dynamics accompanied by a highly competitive landscape owing to its complex and diverse regulatory landscape and varying pharma industry infrastructures across each country, impacting innovation in each country.

Tangential Flow Filtration Market Dynamics:

Drivers:

  1. Growing advantages of tangential flow filtration over normal flow filtration
  2. Rising R&D spending in pharmaceutical & biotechnology industries
  3. Increasing adoption of single-use technologies
  4. Increased adoption of Good Automated Manufacturing Practice (GAMP)

Restraints:

  1. High capital investments for new production facilities to limit the entry of small players

Opportunities:

  1. Emerging economies offer lucrative growth opportunities
  2. Rising therapeutic applications of recombinant proteins

Challenges:

  1. Increased complexities introduced by the interaction of charged excipients and proteins to restrict the market growth
  2. Difficulty in the survival of small players and new entrants

Key Market Players:

Key players in the Market include Merck KGaA (Germany), Danaher Corporation (US), Sartorius AG (Germany), Parker Hannifin Corporation (US), Repligen Corporation (US), Alfa Laval Corporate AB (Sweden), ANDRITZ (Austria) & Others

Recent Developments:

  • In May 2022, Merck KGaA invested over USD 476.7 million to expand its membrane and filtration manufacturing in Ireland.
  • In December 2021, Repligen Corporation acquired Bioflex Solutions, which offers single-use fluid management products.
  • In June 2021, Repligen Corporation signed an agreement to acquire Polymem, which offers hollow-fiber membranes and modules.
  • In March 2021, Pall Corporation acquired Austar Lifesciences Limited. The acquisition aimed to expand the company’s capacity to support single-use technology.

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Contact:
Mr. Aashish Mehra
MarketsandMarkets™ INC. 
630 Dundee Road 
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According to the new market research report “Tangential Flow Filtration Market by Product (System, Membrane Filter), Material (PES, PVDF, PTFE), Technique (Ultrafiltration), Application (Final Product Processing, Raw Material Filtration), End User (Pharma, Biotech), Region – Global Forecast to 2027″, published by MarketsandMarkets™, the global market is projected to reach USD 2.8 billion by 2027 from USD 1.5 billion in 2022, at a CAGR of 13.2% during the forecast period of 2022 to 2027.

Browse in-depth TOC on “Tangential Flow Filtration Market
347 – Tables
45 – Figures
310 – Pages

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The tangential flow filtration industry has grown due to increasing benefits of tangential vs normal flow filtration, rising R&D expenditures in pharmaceutical and biotech sectors, and growing use of single-use technologies. However, high capital investments needed for new production facilities may restrict growth.

The single-use systems segment accounted for the largest share of the product segment in the Tangential Flow filtration market in 2021.

Based on products, the market is segmented into single-use systems, reusable systems, membrane filters, and filtration accessories. In 2021, the single-use systems segment accounted for the largest share of the market and is expected to grow at the highest CAGR during the forecast period. The large share of this segment can primarily be attributed to the minimal chances of cross-contamination risks associated with these systems. The membrane filters market is further segmented into cassettes and capsules & cartridges. In 2021, the cassettes segment accounted for the largest share of the membrane filters market. This can be attributed to the wide usage of cassettes for applications such as separating red blood cells from hemoglobin, clarifying yeast broth and bacterial lysates, and harvesting bacterial, mammalian, and insect cells.

The Microfiltration segment accounted for the largest share of the technique segment in the Tangential Flow filtration market in 2021.

Based on technique, the market is segmented into microfiltration, ultrafiltration, nanofiltration, and other techniques. The microfiltration segment accounted for the largest market share in 2021. The large share of this segment can be attributed to the advantages of microfiltration over other techniques, such as the requirement of low operating pressure, lesser energy consumption, ease of use, cost-effectiveness, the requirement of limited manual actions, elimination of energy-consuming phases such as evaporation, and wide range of applications (from the removal of unwanted suspensions to the removal of bacteria from process liquids).

The Asia Pacific region is the fastest-growing region of the Tangential Flow filtration market in 2021.

Based on the region, the market is segmented into five major regions: North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa. The Asia Pacific is estimated to be the fastest-growing segment of the market. The rising incidence of viral diseases, the rapid expansion of generics production, increasing R&D spending on biopharmaceutical projects, and the growth of the biotechnology industry in developing countries are the major factors contributing to the growth of the Asia Pacific market.

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Key players in the Tangential Flow Filtration Market include Merck KGaA (Germany), Danaher Corporation (US), Sartorius AG (Germany), Parker Hannifin Corporation (US), Repligen Corporation (US), Alfa Laval Corporate AB (Sweden), ANDRITZ (Austria), Meissner Filtration Products, Inc. (US), Cole-Parmer Instrument Company, LLC (US), Solaris Biotechnology Srl (Italy), Koch Separation Solutions (US), Sterlitech Corporation US), Synder Filtration, Inc. (US), PendoTECH (US), ARTeSYN Biosolutions (Ireland), Microfilt India Pvt. Ltd. (India), Bionet (Spain), SYSBIOTECH GmbH (Austria), Cobetter Filtration Equipment Co., Ltd. (China), Biotree (India), FORMULATRIX (US), Mantec Technical Ceramics Ltd. (UK), Smartflow Technologies (US), TAMI Industries (France), and SPF Technologies LLC (US).

Contact:
Mr. Aashish Mehra
MarketsandMarkets™ INC.
630 Dundee Road
Suite 430
Northbrook, IL 60062
USA: +1-888-600-6441
Email: [email protected]

The global tangential flow filtration market is undergoing a rapid transformation, driven by a convergence of factors that are reshaping the landscape of this vital industry. Projections suggest that this market will burgeon to a substantial USD 3.6 billion by 2028, up from USD 1.9 billion in 2023, exhibiting an impressive compound annual growth rate (CAGR) of 13.5%. In this article, we delve into the dynamics of the TFF market, emphasizing technological advancements, the pivotal role of the pharmaceutical and biotechnology sectors, and the challenges that lie ahead.

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Factors Fueling Market Growth

  1. Technological Advancements: One of the primary catalysts propelling the TFF market forward is the continuous evolution of TFF technology. This method has distinct advantages over conventional flow filtration, making it increasingly attractive to various industries. Its ability to separate, concentrate, and purify biomolecules with precision has positioned it as a preferred choice.
  2. Rising R&D Spending: Research and development (R&D) investments are surging across industries, with a particular focus on pharmaceuticals and biotechnology. TFF plays a pivotal role in these sectors, enabling efficient downstream processing and purification of biopharmaceuticals. The demand for TFF products and solutions is directly influenced by the robust R&D activities in these domains.
  3. Growing Pharmaceutical & Biotechnology Industries: The pharmaceutical and biotechnology sectors are experiencing remarkable growth. The demand for biopharmaceuticals and advanced therapies, including cell and gene therapy, is soaring. TFF is indispensable in the production of these therapies, further driving market growth.
  4. Stringent Regulatory Requirements: Regulatory bodies worldwide are placing increased emphasis on product quality and safety, particularly in the pharmaceutical and biotechnology sectors. TFF’s ability to provide precise control and monitoring of processes aligns perfectly with these stringent requirements.

Challenges Ahead

Despite the promising growth prospects, the TFF market faces its share of challenges. One of the most notable obstacles is the high capital investments required to establish new production facilities. These substantial upfront costs can deter potential market entrants and limit market expansion.

Key Players in the TFF Market

Let’s take a closer look at some of the major players in the TFF market and the strategies they employ to maintain their positions:

  1. Danaher Corporation (US): Danaher Corporation stands as a prominent player in the TFF market, known for its robust portfolio of filtration products, including membranes and systems. The company has consistently grown its revenue in recent years through strategic agreements, acquisitions, and expansions. Key developments include agreements with General Electric Life Sciences (US) and Sartorius AG (Germany), positioning Danaher as a key influencer in the TFF industry.
  2. Merck KGaA (Germany): Merck KGaA holds a leading position in the TFF market, offering cutting-edge products for biotechnology and pharmaceutical companies. The company’s strong geographic presence, extensive TFF product portfolio, and continuous expansion in developed and developing regions position it for significant growth in the TFF market. Merck’s emphasis on cell and gene therapy further strengthens its presence in this evolving field.
  3. Sartorius AG (Germany): Sartorius provides a wide range of TFF products catering to biopharmaceutical and pharmaceutical companies, contract manufacturing organizations (CMOs), and contract research organizations (CROs). The company has actively pursued strategic expansion to meet rising demand for its products, especially in the development and manufacturing of COVID-19 therapies and vaccines. Sartorius’ global presence and continuous expansion efforts solidify its position in the TFF market.

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Conclusion

The global TFF market is poised for remarkable growth, driven by technological advancements, increasing R&D investments, and the expanding pharmaceutical and biotechnology sectors. Major players like Danaher Corporation, Merck KGaA, and Sartorius AG are at the forefront of innovation, continuously expanding their portfolios and global presence. As the TFF market evolves, these companies are well-positioned to capitalize on the burgeoning demand for precise and efficient filtration solutions, reaffirming their status as industry leaders.

Contact:
Mr. Aashish Mehra
MarketsandMarkets™ INC.
630 Dundee Road
Suite 430
Northbrook, IL 60062
USA : 1-888-600-6441
[email protected]

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